Dong QiuCardiovascular biomechanics

Cardiovascular biomechanics researcher

Cardiovascular mechanics, from tissue to translation.

I combine experimental mechanics with computational modeling to study cardiovascular tissues, blood flow, and medical devices—linking local behavior to system-level performance.

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Sequential simulated flow fields surrounding moving transcatheter valve leaflets
Simulated flow-field evolution around a transcatheter valve during one cardiac cycle.View source
Current rolePostdoctoral Research FellowUniversity of Denver
Research focusTissues, flow, and devicesCardiovascular biomechanics
Core methodsModel. Measure. Validate.Computational + experimental
Scholarship11 journal articlesSix first-author articles

Selected publications

Selected studies in cardiovascular tissue mechanics, device performance, hemodynamics, and experimental validation.

Finite element views comparing transcatheter valve leaflet geometry and stress for multiple deployment heights
Leaflet geometry and in-plane principal stress across representative deployment configurations.

2025 / Journal of Biomechanics

Can the pinwheeling index serve as a surrogate for accelerated leaflet degeneration in transcatheter heart valves?

Evaluates whether a widely used geometric index reliably reflects leaflet stress patterns associated with degeneration.

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Top views comparing circular complete, eccentric complete, and eccentric incomplete transcatheter valve deployment
Modeled leaflet stress under circular, eccentric, and incomplete deployment conditions.

2021 / Journal of the Mechanical Behavior of Biomedical Materials

Transcatheter aortic valve replacement in bicuspid valves: The synergistic effects of eccentric and incomplete stent deployment

Demonstrates how eccentricity and incomplete expansion combine to alter leaflet stress and motion in bicuspid anatomy.

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Schematic and photograph of a digital image correlation system used for heart valve testing
Experimental workflow for optical measurement of bioprosthetic leaflet mechanics.

2018 / Journal of Biomechanics

High-resolution three-dimensional strain mapping of bioprosthetic heart valves using digital image correlation

Establishes a high-resolution optical workflow for measuring three-dimensional leaflet strain in working bioprosthetic valves.

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Current research

Four connected research areas

Current work spans tissue and vessel mechanics, medical-device performance, hemodynamics, and model validation.

Cardiovascular tissue and vessel mechanics

Measure how vascular, myocardial, and valvular tissues respond across spatial scales and clinically relevant loading conditions.

  • Biaxial testing
  • Digital image correlation
  • Constitutive modeling

Medical-device and intervention mechanics

Study how device geometry, deployment, and anatomy influence performance, durability, and procedural risk.

  • Finite element analysis
  • CT reconstruction
  • ISO 5840 testing

Hemodynamics and flow-structure interaction

Connect flow, tissue motion, and blood stasis to the mechanical behavior of cardiovascular devices.

  • Computational fluid dynamics
  • Fluid-structure interaction
  • Flow-field analysis

Experimental characterization and model validation

Build experimentally informed workflows that connect benchtop measurements with predictive computational models.

  • Pulse-duplicator testing
  • In vitro measurement
  • Model validation
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Academic and research opportunities

Research collaboration and academic opportunities.

I welcome conversations with researchers, clinicians, and engineers working on cardiovascular tissues, blood flow, medical devices, and experimentally validated models.

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